PDBe 1f9r

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF PLATELET FACTOR 4 MUTANT 1

Released:
Source organism: Homo sapiens
Entry authors: Yang J, Doyle M, Faulk T, Visentin G, Aster R, Edwards B

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Platelet factor 4 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 70 amino acids
Theoretical weight: 7.78 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02776 (Residues: 32-101; Coverage: 100%)
Gene names: CXCL4, PF4, SCYB4
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 81.82Å b: 77.48Å c: 43.25Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.224 0.273
Expression system: Escherichia coli