PDBe 1f8a

X-ray diffraction
1.84Å resolution

STRUCTURAL BASIS FOR THE PHOSPHOSERINE-PROLINE RECOGNITION BY GROUP IV WW DOMAINS

Released:

Function and Biology Details

Reaction catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0). 
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Y(SEP)PT(SEP)S PEPTIDE Chain: C
Molecule details ›
Chain: C
Length: 7 amino acids
Theoretical weight: 898 Da
Source organism: Synthetic construct
Expression system: Not provided
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Chain: B
Molecule details ›
Chain: B
Length: 167 amino acids
Theoretical weight: 18.61 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13526 (Residues: 1-163; Coverage: 100%)
Gene name: PIN1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P212121
Unit cell:
a: 35.27Å b: 43.903Å c: 124.659Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.231 0.271
Expression systems:
  • Not provided
  • Escherichia coli