PDBe 1f6d

X-ray diffraction
2.5Å resolution

THE STRUCTURE OF UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE FROM E. COLI.

Released:

Function and Biology Details

Reaction catalysed:
UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-mannosamine. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
UDP-N-acetylglucosamine 2-epimerase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 376 amino acids
Theoretical weight: 42.77 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P27828 (Residues: 1-376; Coverage: 100%)
Gene names: JW5600, b3786, nfrC, rffE, wecB, yifF
Sequence domains: UDP-N-acetylglucosamine 2-epimerase
Structure domains: Glycogen Phosphorylase B;

Ligands and Environments

3 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P21
Unit cell:
a: 91.008Å b: 94.541Å c: 100.97Å
α: 90° β: 109.13° γ: 90°
R-values:
R R work R free
0.198 0.198 0.271
Expression system: Escherichia coli