PDBe 1f5y

Solution NMR

NMR STRUCTURE OF A CONCATEMER OF THE FIRST AND SECOND LIGAND-BINDING MODULES OF THE HUMAN LDL RECEPTOR

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Low-density lipoprotein receptor Chain: A
Molecule details ›
Chain: A
Length: 85 amino acids
Theoretical weight: 9.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01130 (Residues: 21-104; Coverage: 10%)
Gene name: LDLR
Sequence domains: Low-density lipoprotein receptor domain class A
Structure domains: Low-density Lipoprotein Receptor

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Torsion angle dynamics (DYANA) followed by simulated annealing and molecular dynamics (X-PLOR) for calcium coordination
Expression system: Escherichia coli