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SRC SH2 THREF1TRP MUTANT

X-ray diffraction
1.7Å resolution
PDB entry 1f2f coloured by chain, front view.
PDB entry 1f2f coloured by chain, side view.
PDB entry 1f2f coloured by chain, top view.
Source organism: Gallus gallus
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Proto-oncogene tyrosine-protein kinase Src
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Multimeric state: monomeric
Accessible surface area: 6390.58 Å2
Buried surface area: 237.28 Å2
Dissociation area: 118.64 Å2
Dissociation energy (ΔGdiss): 10.14 kcal/mol
Dissociation entropy (TΔSdiss): 0.64 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-132629

Macromolecules

Proto-oncogene tyrosine-protein kinase Src
Chain: A
Length: 104 amino acids
Theoretical weight: 12.06 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: P00523 (Residues: 144-247; Coverage: 20%)
Gene name: SRC
Pfam: SH2 domain
InterPro:
CATH: SH2 domain
SCOP: SH2 domain
Proto-oncogene tyrosine-protein kinase Src in PDB entry 1f2f, assembly 1, front view.
Proto-oncogene tyrosine-protein kinase Src in PDB entry 1f2f, assembly 1, side view.
Proto-oncogene tyrosine-protein kinase Src in PDB entry 1f2f, assembly 1, top view.
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