PDBe 1f2f

X-ray diffraction
1.7Å resolution

SRC SH2 THREF1TRP MUTANT

Released:
Source organism: Gallus gallus

Function and Biology Details

Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. 
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Proto-oncogene tyrosine-protein kinase Src Chain: A
Molecule details ›
Chain: A
Length: 104 amino acids
Theoretical weight: 12.06 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli
UniProt:
  • Canonical: P00523 (Residues: 144-247; Coverage: 20%)
Gene name: SRC
Sequence domains: SH2 domain
Structure domains: SHC Adaptor Protein

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE BW7A
Spacegroup: C2
Unit cell:
a: 74.46Å b: 27.22Å c: 55.25Å
α: 90° β: 106.68° γ: 90°
R-values:
R R work R free
0.208 0.208 0.24
Expression system: Escherichia coli