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CRYSTAL STRUCTURE ANALYSIS OF CRUZAIN BOUND TO VINYL SULFONE DERIVED INHIBITOR (III)

X-ray diffraction
1.8Å resolution
PDB entry 1f2b coloured by chain, front view.
PDB entry 1f2b coloured by chain, side view.
PDB entry 1f2b coloured by chain, top view.
Source organism: Trypanosoma cruzi
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Cruzipain
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-150579

Macromolecules

Cruzipain
Chain: A
Length: 215 amino acids
Theoretical weight: 22.72 KDa
Source organism: Trypanosoma cruzi
Expression system: Escherichia coli
UniProt:
  • Canonical: P25779 (Residues: 123-337; Coverage: 48%)
Pfam: Papain family cysteine protease
InterPro:
CATH: Cysteine proteinases
SCOP: Papain-like
Cruzipain in PDB entry 1f2b, assembly 1, front view.
Cruzipain in PDB entry 1f2b, assembly 1, side view.
Cruzipain in PDB entry 1f2b, assembly 1, top view.
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