PDBe 1exx

X-ray diffraction
1.67Å resolution

ENANTIOMER DISCRIMINATION ILLUSTRATED BY CRYSTAL STRUCTURES OF THE HUMAN RETINOIC ACID RECEPTOR HRARGAMMA LIGAND BINDING DOMAIN: THE COMPLEX WITH THE INACTIVE S-ENANTIOMER BMS270395.

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinoic acid receptor gamma Chain: A
Molecule details ›
Chain: A
Length: 246 amino acids
Theoretical weight: 27.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P13631 (Residues: 178-423; Coverage: 54%)
Gene names: NR1B3, RARG
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID13
Spacegroup: P41212
Unit cell:
a: 59.849Å b: 59.849Å c: 155.615Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.181 0.179 0.243
Expression system: Escherichia coli