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HUMAN LIVER GLYCOGEN PHOSPHORYLASE A COMPLEXED WITH GLCNAC AND CP-403,700

Source organism: Homo sapiens
Biochemical function: SHG alpha-glucan phosphorylase activity
Biological process: necroptotic process
Cellular component: ficolin-1-rich granule lumen

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EC 2.4.1.1: Glycogen phosphorylase

Reaction catalysed:
((1->4)-alpha-D-glucosyl)(n) + phosphate = ((1->4)-alpha-D-glucosyl)(n-1) + alpha-D-glucose 1-phosphate
Systematic name:
(1->4)-alpha-D-glucan:phosphate alpha-D-glucosyltransferase
Alternative Name(s):
  • 1,4-alpha-D-glucan:phosphate alpha-D-glucosyltransferase
  • 1,4-alpha-glucan phosphorylase
  • Alpha-glucan phosphorylase
  • Amylopectin phosphorylase
  • Amylophosphorylase
  • Glucan phosphorylase
  • Glucosan phosphorylase
  • Granulose phosphorylase
  • Maltodextrin phosphorylase
  • Muscle phosphorylase
  • Muscle phosphorylase a and b
  • Myophosphorylase
  • Phosphorylase
  • Polyphosphorylase
  • Potato phosphorylase
  • Starch phosphorylase

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF00343
Domain description: Carbohydrate phosphorylase
Occurring in:
  1. Glycogen phosphorylase, liver form
The deposited structure of PDB entry 1exv contains 2 copies of Pfam domain PF00343 (Carbohydrate phosphorylase) in Glycogen phosphorylase, liver form. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000811
Domain description: Glycosyl transferase, family 35
Occurring in:
  1. Glycogen phosphorylase, liver form
IPR035090
Domain description: Phosphorylase pyridoxal-phosphate attachment site
Occurring in:
  1. Glycogen phosphorylase, liver form
IPR011833
Domain description: Glycogen/starch/alpha-glucan phosphorylase
Occurring in:
  1. Glycogen phosphorylase, liver form

Structure domain

CATH CATH domain
3.40.50.2000
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Glycogen Phosphorylase B;
Occurring in:
  1. Glycogen phosphorylase, liver form
The deposited structure of PDB entry 1exv contains 4 copies of CATH domain 3.40.50.2000 (Rossmann fold) in Glycogen phosphorylase, liver form. Showing 2 copies in chain A.
SCOP SCOP annotation
53766
Class: Alpha and beta proteins (a/b)
Fold: UDP-Glycosyltransferase/glycogen phosphorylase
Superfamily: UDP-Glycosyltransferase/glycogen phosphorylase
Occurring in:
  1. Glycogen phosphorylase, liver form
The deposited structure of PDB entry 1exv contains 2 copies of SCOP domain 53766 (Oligosaccharide phosphorylase) in Glycogen phosphorylase, liver form. Showing 1 copy in chain A.

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