PDBe 1ex0

X-ray diffraction
2Å resolution

HUMAN FACTOR XIII, MUTANT W279F ZYMOGEN

Released:
Source organism: Homo sapiens
Entry authors: Garzon RJ, Pratt KP, Bishop PD, Le Trong I, Stenkamp RE, Teller DC

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Coagulation factor XIII A chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 731 amino acids
Theoretical weight: 83.31 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P00488 (Residues: 2-732; Coverage: 100%)
Gene names: F13A, F13A1
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P21
Unit cell:
a: 100.54Å b: 70.64Å c: 133.38Å
α: 90° β: 106.08° γ: 90°
R-values:
R R work R free
0.187 0.187 0.234
Expression system: Saccharomyces cerevisiae