PDBe 1ew2

X-ray diffraction
1.82Å resolution

CRYSTAL STRUCTURE OF A HUMAN PHOSPHATASE

Released:

Function and Biology Details

Reaction catalysed:
A phosphate monoester + H(2)O = an alcohol + phosphate. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alkaline phosphatase, placental type Chain: A
Molecule details ›
Chain: A
Length: 513 amino acids
Theoretical weight: 55.66 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P05187 (Residues: 23-535; Coverage: 100%)
Gene names: ALPP, PLAP
Sequence domains: Alkaline phosphatase
Structure domains: Alkaline Phosphatase, subunit A

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LURE BEAMLINE D41A
Spacegroup: C2221
Unit cell:
a: 88.8Å b: 114.5Å c: 106.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.185 0.185 0.242