› 1evu

X-ray diffraction
2.01Å resolution

Function and Biology Details

Reaction catalysed: 
A protein-L-glutamine + a protein-L-lysine = a protein with an N(6)-(gamma-glutamyl)-L-lysine cross-link + NH(3)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132554 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Coagulation factor XIII A chain Chains: A, B
Molecule details ›
Chains: A, B
Length: 731 amino acids
Theoretical weight: 83.27 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P00488 (Residues: 2-732; Coverage: 100%)
Gene names: F13A, F13A1
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand CA 2 x CA
Ligand PGO 1 x PGO
1 modified residue:
Ligand SAC 2 x SAC

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P21
Unit cell:
a: 100.172Å b: 70.764Å c: 133.822Å
α: 90° β: 106.11° γ: 90°
R-values:
R R work R free
0.208 0.208 0.266
Expression system: Saccharomyces cerevisiae

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