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CRYSTAL STRUCTURE OF GLUCOSE-FRUCTOSE OXIDOREDUCTASE (GFOR) DELTA1-22 S64D

Source organism: Zymomonas mobilis
Biochemical function: glucose-fructose oxidoreductase activity
Biological process: sorbitol biosynthetic process
Cellular component: periplasmic space

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EC 1.1.99.28: Glucose-fructose oxidoreductase

Reaction catalysed:
D-glucose + D-fructose = D-gluconolactone + D-glucitol
Systematic name:
D-glucose:D-fructose oxidoreductase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF02894
Domain description: Oxidoreductase family, C-terminal alpha/beta domain
Occurring in:
  1. Glucose--fructose oxidoreductase
The deposited structure of PDB entry 1evj contains 4 copies of Pfam domain PF02894 (Oxidoreductase family, C-terminal alpha/beta domain) in Glucose--fructose oxidoreductase. Showing 1 copy in chain A.

PF01408
Domain description: Oxidoreductase family, NAD-binding Rossmann fold
Occurring in:
  1. Glucose--fructose oxidoreductase
The deposited structure of PDB entry 1evj contains 4 copies of Pfam domain PF01408 (Oxidoreductase family, NAD-binding Rossmann fold) in Glucose--fructose oxidoreductase. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR008354
Domain description: Glucose-fructose oxidoreductase, bacterial
Occurring in:
  1. Glucose--fructose oxidoreductase
IPR004104
Domain description: Gfo/Idh/MocA-like oxidoreductase, C-terminal
Occurring in:
  1. Glucose--fructose oxidoreductase
IPR036291
Domain description: NAD(P)-binding domain superfamily
Occurring in:
  1. Glucose--fructose oxidoreductase
IPR000683
Domain description: Gfo/Idh/MocA-like oxidoreductase, N-terminal
Occurring in:
  1. Glucose--fructose oxidoreductase

Structure domains

CATH CATH domains
3.30.360.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Dihydrodipicolinate Reductase; domain 2
Homology: Dihydrodipicolinate Reductase; domain 2
Occurring in:
  1. Glucose--fructose oxidoreductase
The deposited structure of PDB entry 1evj contains 4 copies of CATH domain 3.30.360.10 (Dihydrodipicolinate Reductase; domain 2) in Glucose--fructose oxidoreductase. Showing 1 copy in chain A.
3.40.50.720
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: NAD(P)-binding Rossmann-like Domain
Occurring in:
  1. Glucose--fructose oxidoreductase
The deposited structure of PDB entry 1evj contains 4 copies of CATH domain 3.40.50.720 (Rossmann fold) in Glucose--fructose oxidoreductase. Showing 1 copy in chain A.
SCOP SCOP annotations
51800
Class: Alpha and beta proteins (a/b)
Fold: NAD(P)-binding Rossmann-fold domains
Superfamily: NAD(P)-binding Rossmann-fold domains
Occurring in:
  1. Glucose--fructose oxidoreductase
The deposited structure of PDB entry 1evj contains 4 copies of SCOP domain 51800 (Glyceraldehyde-3-phosphate dehydrogenase-like, N-terminal domain) in Glucose--fructose oxidoreductase. Showing 1 copy in chain A.
55376
Class: Alpha and beta proteins (a+b)
Fold: FwdE/GAPDH domain-like
Superfamily: Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain
Occurring in:
  1. Glucose--fructose oxidoreductase
The deposited structure of PDB entry 1evj contains 4 copies of SCOP domain 55376 (Glucose 6-phosphate dehydrogenase-like) in Glucose--fructose oxidoreductase. Showing 1 copy in chain A.

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