PDBe 1eur

X-ray diffraction
1.82Å resolution

Function and Biology Details

Reaction catalysed:
Hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)- glycosidic linkages of terminal sialic acid residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates. 
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sialidase Chain: A
Molecule details ›
Chain: A
Length: 365 amino acids
Theoretical weight: 38.89 KDa
Source organism: Micromonospora viridifaciens
UniProt:
  • Canonical: Q02834 (Residues: 43-407; Coverage: 60%)
Gene name: nedA
Sequence domains: BNR repeat-like domain
Structure domains: Neuraminidase

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 48.14Å b: 82.73Å c: 84.75Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.173 not available