PDBe 1epv

X-ray diffraction
2.2Å resolution

ALANINE RACEMASE WITH BOUND INHIBITOR DERIVED FROM D-CYCLOSERINE

Released:
Primary publication:
A side reaction of alanine racemase: transamination of cycloserine.
Biochemistry 42 5775-83 (2003)
PMID: 12741835

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alanine racemase Chains: A, B
Molecule details ›
Chains: A, B
Length: 387 amino acids
Theoretical weight: 43.56 KDa
Source organism: Geobacillus stearothermophilus
Expression system: Escherichia coli
UniProt:
  • Canonical: P10724 (Residues: 2-388; Coverage: 100%)
Gene names: alr, dal
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 99.157Å b: 90.243Å c: 85.261Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.206 0.206 0.226
Expression system: Escherichia coli