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HOMOSERINE DEHYDROGENASE FROM S. CEREVISIAE COMPLEX WITH NAD+

X-ray diffraction
2.3Å resolution
PDB entry 1ebf coloured by chain, front view.
PDB entry 1ebf coloured by chain, side view.
PDB entry 1ebf coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Homoserine dehydrogenase
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Multimeric state: homo dimer
Accessible surface area: 29703.6 Å2
Buried surface area: 4189.5 Å2
Dissociation area: 1,577.36 Å2
Dissociation energy (ΔGdiss): 3.12 kcal/mol
Dissociation entropy (TΔSdiss): 14.14 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-151909

Macromolecules

Homoserine dehydrogenase
Chains: A, B
Length: 358 amino acids
Theoretical weight: 38.41 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P31116 (Residues: 2-359; Coverage: 100%)
Gene names: HOM6, J2132, YJR139C
Pfam:
InterPro:
CATH:
SCOP:
Homoserine dehydrogenase in PDB entry 1ebf, assembly 1, front view.
Homoserine dehydrogenase in PDB entry 1ebf, assembly 1, side view.
Homoserine dehydrogenase in PDB entry 1ebf, assembly 1, top view.
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