PDBe 1eb6

X-ray diffraction
1Å resolution

Deuterolysin from Aspergillus oryzae

Released:
Source organism: Aspergillus oryzae

Function and Biology Details

Reaction catalysed:
Preferential cleavage of bonds with hydrophobic residues in P1'; also 3-Asn-|-Gln-4 and 8-Gly-|-Ser-9 bonds in insulin B chain. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutral protease 2 Chain: A
Molecule details ›
Chain: A
Length: 177 amino acids
Theoretical weight: 19.03 KDa
Source organism: Aspergillus oryzae
UniProt:
  • Canonical: P46076 (Residues: 176-352; Coverage: 53%)
Gene name: AO090010000493
Structure domains: Collagenase (Catalytic Domain)

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P21
Unit cell:
a: 38.43Å b: 34.764Å c: 60.276Å
α: 90° β: 106.03° γ: 90°
R-values:
R R work R free
0.104 0.104 0.126