PDBe 1e7v

X-ray diffraction
2.4Å resolution

Structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin and staurosporine


Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: C2
Unit cell:
a: 142.826Å b: 67.334Å c: 106.257Å
α: 90° β: 96.13° γ: 90°
R R work R free
0.273 0.273 0.309
Expression system: Spodoptera frugiperda