PDBe 1e6u

X-ray diffraction
1.45Å resolution

GDP 4-keto-6-deoxy-D-mannose epimerase reductase

Released:

Function and Biology Details

Reaction catalysed:
GDP-beta-L-fucose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + NADPH. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GDP-L-fucose synthase Chain: A
Molecule details ›
Chain: A
Length: 321 amino acids
Theoretical weight: 36.19 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P32055 (Residues: 1-321; Coverage: 100%)
Gene names: JW2037, b2052, fcl, wcaG, yefB
Sequence domains:
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P3221
Unit cell:
a: 102.8Å b: 102.8Å c: 74.9Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.135 0.135 0.17
Expression system: Escherichia coli