PDBe 1e4e

X-ray diffraction
2.5Å resolution

D-alanyl-D-lacate ligase

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vancomycin/teicoplanin A-type resistance protein VanA Chain: A
Molecule details ›
Chain: A
Length: 343 amino acids
Theoretical weight: 37.58 KDa
Source organism: Enterococcus faecium
Expression system: Escherichia coli
UniProt:
  • Canonical: P25051 (Residues: 1-343; Coverage: 100%)
Gene name: vanA
Sequence domains:
Structure domains:
Vancomycin/teicoplanin A-type resistance protein VanA Chain: B
Molecule details ›
Chain: B
Length: 343 amino acids
Theoretical weight: 37.62 KDa
Source organism: Enterococcus faecium
Expression system: Escherichia coli
UniProt:
  • Canonical: P25051 (Residues: 1-343; Coverage: 100%)
Gene name: vanA
Sequence domains:
Structure domains:

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2221
Unit cell:
a: 123.204Å b: 225.359Å c: 72.439Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.183 0.183 0.257
Expression system: Escherichia coli