PDBe 1e3g

X-ray diffraction
2.4Å resolution

human Androgen Receptor Ligand Binding in complex with the ligand metribolone (R1881)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Androgen receptor Chain: A
Molecule details ›
Chain: A
Length: 263 amino acids
Theoretical weight: 30.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P10275 (Residues: 658-920; Coverage: 29%)
Gene names: AR, DHTR, NR3C4
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-4
Spacegroup: P212121
Unit cell:
a: 54.28Å b: 66.14Å c: 71.72Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 0.297
Expression system: Escherichia coli BL21