PDBe 1e2t

X-ray diffraction
2.8Å resolution

Arylamine N-acetyltransferase (NAT) from Salmonella typhimurium

Released:

Function and Biology Details

Reaction catalysed:
Acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo octamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
N-hydroxyarylamine O-acetyltransferase Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 284 amino acids
Theoretical weight: 32.5 KDa
Source organism: Salmonella enterica subsp. enterica serovar Typhimurium
Expression system: Escherichia coli
UniProt:
  • Canonical: Q00267 (Residues: 1-281; Coverage: 100%)
Gene names: STM1582, nhoA
Sequence domains: N-acetyltransferase
Structure domains: Cysteine proteinases

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: P21212
Unit cell:
a: 134.53Å b: 222.419Å c: 104.662Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.264 0.264 0.302
Expression system: Escherichia coli