PDBe 1dxe

X-ray diffraction
1.8Å resolution

2-dehydro-3-deoxy-galactarate aldolase from Escherichia coli

Released:

Function and Biology Details

Reaction catalysed:
2-dehydro-3-deoxy-D-glucarate = pyruvate + tartronate semialdehyde. 
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
5-keto-4-deoxy-D-glucarate aldolase Chains: A, B
Molecule details ›
Chains: A, B
Length: 256 amino acids
Theoretical weight: 27.41 KDa
Source organism: Escherichia coli
UniProt:
  • Canonical: P23522 (Residues: 1-256; Coverage: 100%)
Gene names: JW3095, b3126, garL, yhaF
Sequence domains: HpcH/HpaI aldolase/citrate lyase family
Structure domains: Phosphoenolpyruvate-binding domains

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: R32
Unit cell:
a: 129.07Å b: 129.07Å c: 167.96Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.171 0.171 0.194