PDBe 1dt7

Solution NMR

SOLUTION STRUCTURE OF THE C-TERMINAL NEGATIVE REGULATORY DOMAIN OF P53 IN A COMPLEX WITH CA2+-BOUND S100B(BB)

Released:
Source organisms:
Primary publication:
Structure of the negative regulatory domain of p53 bound to S100B(betabeta).
Nat. Struct. Biol. 7 570-4 (2000)
PMID: 10876243

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cellular tumor antigen p53 Chains: X, Y
Molecule details ›
Chains: X, Y
Length: 22 amino acids
Theoretical weight: 2.6 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P04637 (Residues: 367-388; Coverage: 6%)
Gene names: P53, TP53
Protein S100-B Chains: A, B
Molecule details ›
Chains: A, B
Length: 92 amino acids
Theoretical weight: 10.76 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P04631 (Residues: 1-92; Coverage: 100%)
Gene name: S100b
Sequence domains:
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Expression systems:
  • Not provided
  • Escherichia coli