Function and Biology

STRUCTURE OF HEN EGG-WHITE LYSOZYME

Source organism: Gallus gallus
Biochemical function: hydrolase activity, acting on glycosyl bonds
Biological process: defense response to bacterium
Cellular component: extracellular exosome

EC 3.2.1.17: Lysozyme

Reaction catalysed:
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl- D-glucosamine residues in chitodextrins.
Comments:
Systematic name:
Peptidoglycan N-acetylmuramoylhydrolase
Alternative Name(s):
  • 1,4-N-acetylmuramidase
  • N,O-diacetylmuramidase
  • L-7001
  • PR1-lysozyme
  • Globulin G
  • Globulin G1
  • Lysozyme g
  • Mucopeptide N-acetylmuramoylhydrolase
  • Mucopeptide glucohydrolase
  • Muramidase

Sequence family

CATH Protein family (Pfam)
PF00062
Domain description: C-type lysozyme/alpha-lactalbumin family
Occurring in:
  1. Lysozyme C
1 copy of Pfam domain PF00062 (C-type lysozyme/alpha-lactalbumin family) in Lysozyme C in PDB 1dpx.

CATH InterPro annotations
IPR001916
Domain description: Glycoside hydrolase, family 22
Occurring in:
  1. Lysozyme C
IPR000974
Domain description: Glycoside hydrolase, family 22, lysozyme
Occurring in:
  1. Lysozyme C
IPR030056
Domain description: Lysozyme C
Occurring in:
  1. Lysozyme C
IPR019799
Domain description: Glycoside hydrolase, family 22, conserved site
Occurring in:
  1. Lysozyme C
IPR023346
Domain description: Lysozyme-like domain
Occurring in:
  1. Lysozyme C

Structure domain

CATH CATH domain
1.10.530.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Lysozyme
Homology: Lysozyme
Occurring in:
  1. Lysozyme C
1 copy of CATH domain 1.10.530.10 (Lysozyme) in Lysozyme C in PDB 1dpx.
SCOP SCOP annotation
53960
Class: Alpha and beta proteins (a+b)
Fold: Lysozyme-like
Superfamily: Lysozyme-like
Occurring in:
  1. Lysozyme C
1 copy of SCOP domain 53960 (C-type lysozyme) in Lysozyme C in PDB 1dpx.