PDBe 1dp7

X-ray diffraction
1.5Å resolution

COCRYSTAL STRUCTURE OF RFX-DBD IN COMPLEX WITH ITS COGNATE X-BOX BINDING SITE

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct DNA molecule
Macromolecules (2 distinct):
MHC class II regulatory factor RFX1 Chain: P
Molecule details ›
Chain: P
Length: 76 amino acids
Theoretical weight: 8.83 KDa
Source organism: Synthetic construct
Expression system: Not provided
UniProt:
  • Canonical: P22670 (Residues: 438-513; Coverage: 8%)
Gene name: RFX1
Structure domains: "winged helix" repressor DNA binding domain
DNA (5'-D(*CP*GP*(BRU)P*TP*AP*CP*CP*AP*(BRU)P*GP*GP*TP*AP*AP*CP*G)-3') Chain: D
Molecule details ›
Chain: D
Length: 16 nucleotides
Theoretical weight: 5.03 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2, NSLS BEAMLINE X9A
Spacegroup: C2
Unit cell:
a: 72.843Å b: 42.752Å c: 52.277Å
α: 90° β: 109.21° γ: 90°
R-values:
R R work R free
0.192 0.192 0.228
Expression system: Not provided