PDBe 1dhr

X-ray diffraction
2.3Å resolution

CRYSTAL STRUCTURE OF RAT LIVER DIHYDROPTERIDINE REDUCTASE

Released:
Source organism: Rattus norvegicus
Primary publication:
Crystal structure of rat liver dihydropteridine reductase.
Proc. Natl. Acad. Sci. U.S.A. 89 6080-4 (1992)
PMID: 1631094

Function and Biology Details

Reaction catalysed:
A 5,6,7,8-tetrahydropteridine + NAD(P)(+) = a 6,7-dihydropteridine + NAD(P)H. 
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dihydropteridine reductase Chain: A
Molecule details ›
Chain: A
Length: 241 amino acids
Theoretical weight: 25.58 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
  • Canonical: P11348 (Residues: 1-241; Coverage: 100%)
Gene names: Dhpr, Qdpr
Sequence domains: short chain dehydrogenase
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2221
Unit cell:
a: 50.1Å b: 139.13Å c: 64.93Å
α: 90° β: 90° γ: 90°
Expression system: Not provided