Structure analysis

DIHYDRODIPICOLINATE SYNTHASE

X-ray diffraction
2.3Å resolution
Source organism: Escherichia coli
Assemblies composition:
homo tetramer
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1
Download    3D Visualisation
Multimeric state: homo tetramer
Accessible surface area: 39800 Å2
Buried surface area: 8100 Å2
Dissociation area: 950 Å2
Dissociation energy (ΔGdiss): -4 kcal/mol
Dissociation entropy (TΔSdiss): 15 kcal/mol
Interface energy (ΔGint): -399 kcal/mol
Symmetry number: 4
Assembly 2 (preferred)
Download    3D Visualisation
Multimeric state: homo dimer
Accessible surface area: 11700 Å2
Buried surface area: 250 Å2
Dissociation area: 100 Å2
Dissociation energy (ΔGdiss): 91 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Interface energy (ΔGint): -91 kcal/mol
Symmetry number: 1

Macromolecules

Chains: A, B
Length: 292 amino acids
Theoretical weight: 31.3 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0A6L2 (Residues: 1-292; Coverage: 100%)
Gene names: JW2463, b2478, dapA
Pfam: Dihydrodipicolinate synthetase family
InterPro:
CATH: Aldolase class I
SCOP: Class I aldolase

Search similar proteins