PDBe 1dhk

X-ray diffraction
1.85Å resolution

STRUCTURE OF PORCINE PANCREATIC ALPHA-AMYLASE

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Alpha-amylase inhibitor 1 Chain: B
Molecule details ›
Chain: B
Length: 223 amino acids
Theoretical weight: 24.81 KDa
Source organism: Phaseolus vulgaris
UniProt:
  • Canonical: P02873 (Residues: 24-246; Coverage: 100%)
Gene names: Alpha-AI1, LLP
Sequence domains: Legume lectin domain
Structure domains: Jelly Rolls
Pancreatic alpha-amylase Chain: A
Molecule details ›
Chain: A
Length: 496 amino acids
Theoretical weight: 55.4 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P00690 (Residues: 16-511; Coverage: 100%)
Gene name: AMY2
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: C2
Unit cell:
a: 151.6Å b: 79.4Å c: 68Å
α: 90° β: 91.54° γ: 90°
R-values:
R R work R free
0.183 0.183 0.22