PDBe 1df0

X-ray diffraction
2.6Å resolution

Crystal structure of M-Calpain

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calpain small subunit 1 Chain: B
Molecule details ›
Chain: B
Length: 184 amino acids
Theoretical weight: 21.3 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q64537 (Residues: 88-270; Coverage: 68%)
Gene names: Capn4, Capns1, Css1
Sequence domains: EF-hand domain pair
Structure domains: EF-hand
Calpain-2 catalytic subunit Chain: A
Molecule details ›
Chain: A
Length: 700 amino acids
Theoretical weight: 79.99 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q07009 (Residues: 1-700; Coverage: 100%)
Gene name: Capn2
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F2
Spacegroup: P1
Unit cell:
a: 57.696Å b: 80.181Å c: 80.72Å
α: 60.371° β: 70.848° γ: 79.486°
R-values:
R R work R free
0.223 0.223 0.293
Expression system: Escherichia coli