PDBe 1d8t

X-ray diffraction
2.35Å resolution

CRYSTAL STRUCTURE OF ELONGATION FACTOR, TU (EF-TU-MGGDP) COMPLEXED WITH GE2270A, A THIAZOLYL PEPTIDE ANTIBIOTIC

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Thiocillin GE2270 Chains: C, D
Molecule details ›
Chains: C, D
Length: 15 amino acids
Theoretical weight: 1.48 KDa
Source organism: Planobispora rosea
UniProt:
  • Canonical: Q7M0J8 (Residues: 1-14; Coverage: 100%)
Elongation factor Tu 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 393 amino acids
Theoretical weight: 43.21 KDa
Source organism: Escherichia coli
UniProt:
  • Canonical: P0CE47 (Residues: 2-393; Coverage: 100%)
Gene names: JW3301, b3339, tufA
Sequence domains:
Structure domains:

Ligands and Environments

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: C2
Unit cell:
a: 133.47Å b: 45.17Å c: 144Å
α: 90° β: 94.64° γ: 90°
R-values:
R R work R free
0.2 0.2 0.246