PDBe 1d4w

X-ray diffraction
1.8Å resolution

CRYSTAL STRUCTURE OF THE XLP PROTEIN SAP IN COMPLEX WITH SLAM PHOSPHOPEPTIDE

Released:

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
SH2 domain-containing protein 1A Chains: A, B
Molecule details ›
Chains: A, B
Length: 104 amino acids
Theoretical weight: 11.7 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O60880 (Residues: 1-104; Coverage: 81%)
Gene names: DSHP, SAP, SH2D1A
Sequence domains: SH2 domain
Structure domains: SHC Adaptor Protein
Signaling lymphocytic activation molecule Chains: C, D
Molecule details ›
Chains: C, D
Length: 11 amino acids
Theoretical weight: 1.36 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q13291 (Residues: 276-286; Coverage: 4%)
Gene names: SLAM, SLAMF1

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: C2
Unit cell:
a: 100.2Å b: 49Å c: 55.6Å
α: 90° β: 94.2° γ: 90°
R-values:
R R work R free
0.172 0.153 0.24
Expression systems:
  • Escherichia coli
  • Not provided