PDBe 1cvr

X-ray diffraction
2Å resolution

Crystal structure of the Arg specific cysteine proteinase gingipain R (RGPB)

Released:

Function and Biology Details

Reaction catalysed:
Hydrolysis of proteins and small molecule substrates, with a preference for Arg in P1. 
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gingipain R2 Chain: A
Molecule details ›
Chain: A
Length: 435 amino acids
Theoretical weight: 47.93 KDa
Source organism: Porphyromonas gingivalis
Expression system: Not provided
UniProt:
  • Canonical: P95493 (Residues: 230-664; Coverage: 61%)
Gene names: PG_0506, prtRII, rgp2, rgpB
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 51.93Å b: 79.92Å c: 99.82Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.163 0.163 0.207
Expression system: Not provided