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DETERMINATION OF THE SOLUTION STRUCTURE OF A SYNTHETIC TWO-SITE CALCIUM-BINDING HOMODIMERIC PROTEIN DOMAIN BY NMR SPECTROSCOPY

Solution NMR
PDB entry 1cta coloured by chain, front view.
PDB entry 1cta coloured by chain, side view.
PDB entry 1cta coloured by chain, top view.
Source organism: Gallus gallus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Troponin C, skeletal muscle
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Multimeric state: homo dimer
Accessible surface area: 4691.09 Å2
Buried surface area: 1865.3 Å2
Dissociation area: 677.06 Å2
Dissociation energy (ΔGdiss): 7.89 kcal/mol
Dissociation entropy (TΔSdiss): 9.19 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-135944

Macromolecules

Troponin C, skeletal muscle
Chains: A, B
Length: 36 amino acids
Theoretical weight: 3.86 KDa
Source organism: Gallus gallus
Expression system: Not provided
UniProt:
  • Canonical: P02588 (Residues: 94-127; Coverage: 21%)
Gene name: TNNC2
Pfam: EF hand
InterPro:
SCOP: Calmodulin-like
Troponin C, skeletal muscle in PDB entry 1cta, assembly 1, front view.
Troponin C, skeletal muscle in PDB entry 1cta, assembly 1, side view.
Troponin C, skeletal muscle in PDB entry 1cta, assembly 1, top view.
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