PDBe 1cm8

X-ray diffraction
2.4Å resolution

PHOSPHORYLATED MAP KINASE P38-GAMMA

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mitogen-activated protein kinase 12 Chains: A, B
Molecule details ›
Chains: A, B
Length: 367 amino acids
Theoretical weight: 42.16 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P53778 (Residues: 1-367; Coverage: 100%)
Gene names: ERK6, MAPK12, SAPK3
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

2 bound ligands:

2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: P212121
Unit cell:
a: 63.5Å b: 66.82Å c: 206.02Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.232 0.283
Expression system: Escherichia coli