PDBe 1ckx

Solution NMR

Cystic fibrosis transmembrane conductance regulator: Solution structures of peptides based on the Phe508 region, the most common site of disease-causing Delta-F508 mutation


Function and Biology Details

Reaction catalysed:
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Cystic fibrosis transmembrane conductance regulator Chain: A
Molecule details ›
Chain: A
Length: 26 amino acids
Theoretical weight: 3.05 KDa
Source organism: Ovis aries
Expression system: Not provided
  • Canonical: Q00555 (Residues: 497-522; Coverage: 2%)
Gene names: ABCC7, CFTR

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 44%
Refinement method: distance geometry
Chemical shifts: BMR4596  
Expression system: Not provided