EC 3.1.1.5: Lysophospholipase
Reaction catalysed:
2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate
Systematic name:
2-lysophosphatidylcholine acylhydrolase
Alternative Name(s):
- Lecithinase B
- Lecitholipase
- Lysolecithinase
- Lysophopholipase L2
- Lysophosphatidase
- Lysophosphatidylcholine hydrolase
- Lysophospholipase A1
- Phosphatidase B
- Phospholipase B
EC 3.1.1.4: Phospholipase A(2)
Reaction catalysed:
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate
Systematic name:
Phosphatidylcholine 2-acylhydrolase
Alternative Name(s):
- Lecithinase A
- Phosphatidase
- Phosphatidolipase
- Phospholipase A
- Phospholipase A2
GO terms
Biochemical function:
- ceramide 1-phosphate binding
- phosphatidyl phospholipase B activity
- phosphatidylinositol-4-phosphate binding
- carboxylic ester hydrolase activity
- calcium-independent phospholipase A2 activity
- calcium-dependent phospholipase A2 activity
- metal ion binding
- phosphatidylinositol-3-phosphate binding
- hydrolase activity
- phosphatidylinositol-5-phosphate binding
- O-acyltransferase activity
- lipid binding
- calcium-dependent phospholipid binding
- calcium ion binding
- phospholipase A2 activity
- lysophospholipase activity
- phospholipase activity
Biological process:
- cellular response to antibiotic
- establishment of localization in cell
- arachidonic acid secretion
- glycerophospholipid catabolic process
- icosanoid biosynthetic process
- positive regulation of macrophage activation
- regulation of cell population proliferation
- phosphatidylcholine acyl-chain remodeling
- phosphatidylcholine catabolic process
- phosphatidylglycerol catabolic process
- positive regulation of prostaglandin secretion
- leukotriene biosynthetic process
- arachidonic acid metabolic process
- lipid catabolic process
- positive regulation of platelet activation
- phospholipid catabolic process
- prostaglandin metabolic process
- icosanoid metabolic process
- platelet activating factor biosynthetic process
- glycerophospholipid metabolic process
- monoacylglycerol biosynthetic process
- fatty acid biosynthetic process
- fatty acid metabolic process
- lipid metabolic process
- glycerol metabolic process
- positive regulation of T-helper 1 type immune response
- prostaglandin biosynthetic process
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotationsStructure domains
CATH domains
3.40.1090.10
Class:
Alpha Beta
Architecture:
3-Layer(aba) Sandwich
Topology:
Cytosolic phospholipase A2 catalytic domain
Homology:
Cytosolic phospholipase A2 catalytic domain
Occurring in:
SCOP annotations
