PDBe 1cff

Solution NMR

NMR SOLUTION STRUCTURE OF A COMPLEX OF CALMODULIN WITH A BINDING PEPTIDE OF THE CA2+-PUMP

Released:

Function and Biology Details

Reaction catalysed:
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2). 
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin-2 A Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 16.72 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DP34 (Residues: 2-149; Coverage: 99%)
Gene name: calm2-a
Structure domains: EF-hand
Plasma membrane calcium-transporting ATPase 4 Chain: B
Molecule details ›
Chain: B
Length: 20 amino acids
Theoretical weight: 2.5 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P23634 (Residues: 1086-1104; Coverage: 2%)
Gene names: ATP2B2, ATP2B4, MXRA1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 82%
Refinement method: simulated annealing
Chemical shifts: BMR5480  
Expression system: Escherichia coli