› 1cf1

X-ray diffraction
2.8Å resolution

ARRESTIN FROM BOVINE ROD OUTER SEGMENTS

Released:
DOI: 10.2210/pdb1cf1/pdb
PDB entry 1cf1 coloured by chain, front view.
PDB entry 1cf1 coloured by chain, side view.
PDB entry 1cf1 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation.
Hirsch JA, Schubert C, Gurevich VV, Sigler PB
Cell 97 257-69 (1999)
PMID: 10219246

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-139948 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
S-arrestin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 404 amino acids
Theoretical weight: 45.26 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P08168 (Residues: 2-404; Coverage: 100%)
Gene name: SAG
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: C2221
Unit cell:
a: 168.85Å b: 193.19Å c: 191.12Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.233 0.233 0.244
Expression system: Escherichia coli

Quick links

Citations

60 review citations

Beta-arrestins and cell signaling.
DeWire et al. (2007)
59 more

63 mentions without citation

The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling.
Peterson et al. (2017)
62 more