PDBe 1cdm

X-ray diffraction
2Å resolution

MODULATION OF CALMODULIN PLASTICITY IN MOLECULAR RECOGNITION ON THE BASIS OF X-RAY STRUCTURES

Released:

Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein. 

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calcium/calmodulin-dependent protein kinase type II subunit alpha Chain: B
Molecule details ›
Chain: B
Length: 25 amino acids
Theoretical weight: 2.89 KDa
Source organism: Rattus norvegicus
Expression system: Not provided
UniProt:
  • Canonical: P11275 (Residues: 290-314; Coverage: 5%)
Gene name: Camk2a
Calmodulin Chain: A
Molecule details ›
Chain: A
Length: 144 amino acids
Theoretical weight: 16.28 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P62157 (Residues: 5-148; Coverage: 97%)
Gene names: CALM, CAM
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2221
Unit cell:
a: 39Å b: 75.2Å c: 120.15Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.208 not available
Expression system: Not provided