PDBe 1cdl

X-ray diffraction
2Å resolution

TARGET ENZYME RECOGNITION BY CALMODULIN: 2.4 ANGSTROMS STRUCTURE OF A CALMODULIN-PEPTIDE COMPLEX

Released:

Function and Biology Details

Reaction catalysed:
ATP + [myosin light-chain] = ADP + [myosin light-chain] phosphate. 
Biochemical function:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Calmodulin-2 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 147 amino acids
Theoretical weight: 16.59 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P0DP24 (Residues: 2-148; Coverage: 99%)
Gene names: CALM2, CAM2, CAMB
Structure domains: EF-hand
Myosin light chain kinase, smooth muscle, deglutamylated form Chains: E, F, G, H
Molecule details ›
Chains: E, F, G, H
Length: 20 amino acids
Theoretical weight: 2.29 KDa
Source organism: Gallus gallus
Expression system: Not provided
UniProt:
  • Canonical: P11799 (Residues: 1730-1749; Coverage: 1%)
Gene name: Mylk

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P21212
Unit cell:
a: 166.1Å b: 104.9Å c: 43.32Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.208 not available
Expression system: Not provided