EC 188.8.131.52: Quinoprotein glucose dehydrogenase (PQQ, quinone)
D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol.
- Integral membrane protein containing PQQ as prosthetic group.
- It also contains bound ubiquinone and Mg(2+) or Ca(2+).
- Electron acceptor is membrane ubiquinone but usually assayed with phenazine methosulfate.
- Like in all other quinoprotein alcohol dehydrogenases the catalytic domain has an 8-bladed 'propeller' structure.
- It occurs in a wide range of bacteria.
- Catalyzes a direct oxidation of the pyranose form of D-glucose to the lactone and thence to D-gluconate in the periplasm.
- Oxidizes other monosaccharides including the pyranose forms of pentoses.
- Formerly EC 184.108.40.206.
- D-glucose:(pyrroloquinoline-quinone) 1-oxidoreductase
- Glucose dehydrogenase (PQQ-dependent)
- Glucose dehydrogenase (pyrroloquinoline-quinone)
- Quinoprotein D-glucose dehydrogenase
- Membrane-bound glucose dehydrogenase
Protein family (Pfam)
Domain description: Glucose / Sorbosone dehydrogenase
Domain description: Glucose/Sorbosone dehydrogenase
Domain description: PQQ-dependent dehydrogenase, s-GDH family
Domain description: Soluble quinoprotein glucose/sorbosone dehydrogenase
Domain description: Six-bladed beta-propeller, TolB-like
Class: Mainly Beta
Architecture: 6 Propellor
Homology: TolB, C-terminal domainOccurring in:
Class: All beta proteins
Fold: 6-bladed beta-propeller
Superfamily: Soluble quinoprotein glucose dehydrogenaseOccurring in: