PDBe 1c7r

X-ray diffraction
2.5Å resolution

THE CRYSTAL STRUCTURE OF PHOSPHOGLUCOSE ISOMERASE/AUTOCRINE MOTILITY FACTOR/NEUROLEUKIN COMPLEXED WITH ITS CARBOHYDRATE PHOSPHATE INHIBITORS AND ITS SUBSTRATE RECOGNITION MECHANISM

Released:

Function and Biology Details

Reaction catalysed:
D-glucose 6-phosphate = D-fructose 6-phosphate
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glucose-6-phosphate isomerase B Chain: A
Molecule details ›
Chain: A
Length: 445 amino acids
Theoretical weight: 50.2 KDa
Source organism: Geobacillus stearothermophilus
Expression system: Escherichia coli
UniProt:
  • Canonical: P13376 (Residues: 1-445; Coverage: 100%)
Gene name: pgiB
Sequence domains: Phosphoglucose isomerase
Structure domains: Glucose-6-phosphate isomerase like protein; domain 1

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: I222
Unit cell:
a: 74.8Å b: 94.71Å c: 171.74Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.215 0.215 0.289
Expression system: Escherichia coli