› 1bz5

X-ray diffraction
2.58Å resolution

EVIDENCE OF A COMMON DECAMER IN THREE CRYSTAL STRUCTURES OF BPTI, CRYSTALLIZE FROM THIOCYANATE, CHLORIDE OR SULFATE

Released:
DOI: 10.2210/pdb1bz5/pdb
PDB entry 1bz5 coloured by chain, front view.
PDB entry 1bz5 coloured by chain, side view.
PDB entry 1bz5 coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
The BPTI decamer observed in acidic pH crystal forms pre-exists as a stable species in solution.
Hamiaux C, Pérez J, Prangé T, Veesler S, Riès-Kautt M, Vachette P
J Mol Biol 297 697-712 (2000)
PMID: 10731422

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo decamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133761 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pancreatic trypsin inhibitor Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 58 amino acids
Theoretical weight: 6.53 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P00974 (Residues: 36-93; Coverage: 73%)
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Structure domains: Pancreatic trypsin inhibitor Kunitz domain

Ligands and Environments

1 bound ligand:
Ligand SO4 3 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LURE BEAMLINE DW32
Spacegroup: P6322
Unit cell:
a: 120.48Å b: 120.48Å c: 111.3Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.19 0.19 0.218

Quick links

Citations

2 review citations

Structural characterization of proteins and complexes using small-angle X-ray solution scattering.
Mertens et al. (2010)
1 more