PDBe 1byg

X-ray diffraction
2.4Å resolution

KINASE DOMAIN OF HUMAN C-TERMINAL SRC KINASE (CSK) IN COMPLEX WITH INHIBITOR STAUROSPORINE

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine-protein kinase CSK Chain: A
Molecule details ›
Chain: A
Length: 278 amino acids
Theoretical weight: 31.18 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P41240 (Residues: 173-450; Coverage: 62%)
Gene name: CSK
Sequence domains: Protein tyrosine kinase
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21212
Unit cell:
a: 44.49Å b: 120.58Å c: 48.29Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.199 0.287
Expression system: Escherichia coli