Structure analysis

PROBING THE SUBSTRATE SPECIFICITY OF THE INTRACELLULAR BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE

X-ray diffraction
2.1Å resolution
Source organism: Bos taurus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
Download
Multimeric state: homo dimer
Accessible surface area: 17700 Å2
Buried surface area: 2300 Å2
Dissociation area: 1,100 Å2
Dissociation energy (ΔGdiss): 2 kcal/mol
Dissociation entropy (TΔSdiss): 13 kcal/mol
Interface energy (ΔGint): -7 kcal/mol
Symmetry number: 2

Macromolecules

Chain: A
Length: 233 amino acids
Theoretical weight: 25.96 KDa
Source organism: Bos taurus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q29460 (Residues: 1-232; Coverage: 100%)
Gene names: PAFAH1B3, PAFAHG
Pfam: GDSL-like Lipase/Acylhydrolase family
InterPro: SGNH hydrolase-type esterase domain
CATH: Rossmann fold
SCOP: Acetylhydrolase

Search similar proteins