› 1bpi

X-ray diffraction
1.09Å resolution

THE STRUCTURE OF BOVINE PANCREATIC TRYPSIN INHIBITOR AT 125K: DEFINITION OF CARBOXYL-TERMINAL RESIDUES GLYCINE-57 AND ALANINE-58

Released:
DOI: 10.2210/pdb1bpi/pdb
PDB entry 1bpi coloured by chain, front view.
PDB entry 1bpi coloured by chain, side view.
PDB entry 1bpi coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Structure of bovine pancreatic trypsin inhibitor at 125 K definition of carboxyl-terminal residues Gly57 and Ala58.
Parkin S, Rupp B, Hope H
Acta Crystallogr D Biol Crystallogr 52 18-29 (1996)
PMID: 15299722

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133749 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Pancreatic trypsin inhibitor Chain: A
Molecule details ›
Chain: A
Length: 58 amino acids
Theoretical weight: 6.53 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P00974 (Residues: 36-93; Coverage: 73%)
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Structure domains: Pancreatic trypsin inhibitor Kunitz domain

Ligands and Environments

1 bound ligand:
Ligand PO4 1 x PO4
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 75.39Å b: 22.581Å c: 28.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 not available not available
Expression system: Not provided

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Citations

2 review citations

The benefits of atomic resolution.
Dauter et al. (1997)
1 more

50 mentions without citation

TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections.
Shen et al. (2017)
49 more