PDBe 1bph

X-ray diffraction
2Å resolution

CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11

Released:
Source organism: Bos taurus
Primary publication:
Conformational changes in cubic insulin crystals in the pH range 7-11.
Biophys. J. 63 1210-20 (1992)
PMID: 1477273

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Structure domain:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Insulin A chain Chain: A
Molecule details ›
Chain: A
Length: 21 amino acids
Theoretical weight: 2.34 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P01317 (Residues: 85-105; Coverage: 26%)
Gene name: INS
Insulin B chain Chain: B
Molecule details ›
Chain: B
Length: 30 amino acids
Theoretical weight: 3.4 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P01317 (Residues: 25-54; Coverage: 37%)
Gene name: INS

Ligands and Environments

2 bound ligands:

No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: I213
Unit cell:
a: 78.9Å b: 78.9Å c: 78.9Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.16 not available not available
Expression system: Not provided