PDBe 1blx

X-ray diffraction
1.9Å resolution

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Cyclin-dependent kinase 4 inhibitor D Chain: B
Molecule details ›
Chain: B
Length: 166 amino acids
Theoretical weight: 17.83 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q60773 (Residues: 1-166; Coverage: 100%)
Gene name: Cdkn2d
Sequence domains: Ankyrin repeats (3 copies)
Structure domains: Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
Cyclin-dependent kinase 6 Chain: A
Molecule details ›
Chain: A
Length: 326 amino acids
Theoretical weight: 36.99 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q00534 (Residues: 1-326; Coverage: 100%)
Gene names: CDK6, CDKN6
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: P212121
Unit cell:
a: 74.21Å b: 76.41Å c: 93.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.2 0.253
Expression systems:
  • Escherichia coli BL21(DE3)
  • Spodoptera frugiperda