› 1bjz

X-ray diffraction
2.2Å resolution

TETRACYCLINE CHELATED MG2+-ION INITIATES HELIX UNWINDING FOR TET REPRESSOR INDUCTION

Released:
DOI: 10.2210/pdb1bjz/pdb
PDB entry 1bjz coloured by chain, front view.
PDB entry 1bjz coloured by chain, side view.
PDB entry 1bjz coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Tetracycline-chelated Mg2+ ion initiates helix unwinding in Tet repressor induction.
Orth P, Saenger W, Hinrichs W
Biochemistry 38 191-8 (1999)
PMID: 9890898

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-142298 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tetracycline repressor protein class D Chain: A
Molecule details ›
Chain: A
Length: 207 amino acids
Theoretical weight: 23.29 KDa
Source organism: Escherichia coli
Expression system: Not provided
UniProt:
  • Canonical: P0ACT4 (Residues: 2-208; Coverage: 95%)
Gene name: tetR
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.5
Spacegroup: I4122
Unit cell:
a: 69.1Å b: 69.1Å c: 182.93Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.232 0.296
Expression system: Not provided

Quick links

Citations

6 review citations

Coordination chemistry of bacterial metal transport and sensing.
Ma et al. (2009)
5 more

5 mentions without citation

The TetR family of transcriptional repressors.
Ramos et al. (2005)
4 more